Science is intrinsically hard and confronts us with our absolute stupidity on a daily basis. This poses a high mental pressure especially on younger researchers. It just underlines the importance of being able to deal with stress and other mental issues. But it is also important to keep in mind that questions we are trying to answer are the kind of questions no one can answer yet. This is what research is about. Asking new questions and finding new answers. So this is also a call to everyone: Let us all be open about the things we do not know. Not knowing in our profession does not mean we are not as smart as others, but that we are asking questions no one was able to answer yet.
A very interesting article on this topic can be found here